A degeneration or damage of the peripheral nerves. The most common type seen in HIV infection occurs at the end of the nerve, affecting the soles of the feet, tips of the toes or tips of the fingers. Symptoms include numbness, tingling, a burning sensation, sensitivity and sometimes pain. In advanced cases these may be accompanied by leg and arm weakness. Peripheral neuropathy may be a reaction to HIV antiretroviral treatment or HIV itself may be responsible.