Cross Resistance

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Cross resistance develops when a virus mutates (changes) so that is it is resistant to more than one drug. This can occur when two drugs of the same class (type) have very similar chemical compositions, whereby resistance to one of those drugs may also mean resistance to the other drug, due to their similarity. Your doctor will advise if drug resistance is present, by conducting a resistance test, but good adherence (taking your HIV ARV treatments daily as prescribed) prevents drug resistance occurring mostly. If resistance is high (and your treatments stop working effectively), your doctor will advise about other treatment options – sometimes a different drug class (type) may need to be used if there is cross resistance present.