NEW LONG ACTING HIV DRUG CLASS ON THE HORIZON – CAPSID INHIBITORS

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Capsid assembly is the step in the HIV lifecycle where the virus develops a cone-shaped core (capsid) particle, which contains or encloses the viral genetic blueprint (genome), inside a maturing infectious virion. It consists of a protein envelop membrane which protects the viral antigen core genetic proteins (called “p24”). Once released inside the host human cell, the core capsid particle disassembles to allow the... Read more

Bictegravir – A new Integrase Inhibitor in the pipeline

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Bictegravir matches dolutegravir for first-line treatment in Phase 2 studies Paul Sax at CROI 2017. Photo by Liz Highleyman, hivandhepatitis.com Bictegravir, an investigational new integrase inhibitor, was highly potent, well tolerated and worked as well as dolutegravir (Tivicay – an existing integrase inhibitor) in a phase 2 clinical trial of people first starting treatment, according to study results... Read more

Doravirine – a new NNRTI (Non-Nuke) option on the horizon

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Kathleen Squires at CROI 2017. Photo by Liz Highleyman, hivandhepatitis.com Doravirine, an investigational next-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) that reduced HIV viral load as well as boosted darunavir (a Protease Inhibitor) in a phase 3 clinical trial of people starting HIV treatment for the first time; but it had a better lipid (blood fat) profile, according to a late breaking... Read more

What is safe sex now? Does it include undetectable viral load and PrEP?

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Treatment as prevention and pre-exposure prophylaxis (PrEP) provide new ways to safely avoid HIV, but this poses challenges to the ways in which communities understand and practice ‘safe sex’, Martin Holt of the University of New South Wales told a public lecture in Sydney last week. Gay men’s awareness and understanding of the new prevention methods has developed rapidly, but history suggests that people may... Read more

What is the National Disability Insurance Scheme (NDIS)? How does it apply to PLHIV?

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The National Disability Insurance Scheme (NDIS) is a new commonwealth support program for people under 65yo with a permanent disability impairment that affects activities of functional daily living. The program is now being progressively rolled out across Australian states and territories, with full national implementation expected by 2020, and is currently rolling out in Queensland. The scheme aims to link under 65yo... Read more

Aged Care Reforms – Increasing choice in home care

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As the HIV-positive population ages through the life-extending benefits of HIV treatments, age-related illness will (and already have) become an increasing concern, such as heart disease, diabetes, kidney disease, bone density loss, and some cancers. Alongside of this medication and treatment needs will increase, bringing their own complications (such as drug interactions, increased pill burden, side effects, etc).  As... Read more

Positively Quitting…You’ll be glad you did!

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Over recent years, there have been tremendous gains and improvements in HIV treatment, which have extended life expectancy and the quality of life for people living with HIV (PLHIV). In Queensland, the number of new HIV diagnoses fell 21% within 2 years (from 2014 to 2016), and HIV-related deaths are basically a thing of the past through the benefits of early uptake of treatment. Yet cigarette smoking is still excessively... Read more

RAPID’s GeneXpert trial Update

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We are pleased to provide an update regarding the commencement of RAPID’s revolutionary STI testing project using GeneXpert technology, as announced by QPP in November 2016. The research pilot, involving partners from QPP, the University of Queensland School of Public Health, Metro North HHS and funded by Metro North LINK innovation funding, will see RAPID offer point of care testing for chlamydia and gonorrhoea (the... Read more

Increase in Pbs Prescription Co-Payments and Safety Net Thresholds From 01 January, 2017

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On 01 January 2017 the annual increase to the cost of Pharmaceutical Benefits Scheme (PBS) co-payments for medicines (treatments), and the PBS Safety Net Thresholds, came into effect, as follows: 2016 2017 PBS Co-payment Increase General Patients $38.30 $38.80 $0.50 cents Concessional Patients (Holders of a Centrelink Concession Card) $6.20 $6.30 $0.10 cents   The 2017 PBS... Read more

Peer Support Group Update

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QPP have been helping to coordinate monthly social events for People Living with HIV (PLHIV) across Queensland. We are expecting to extend social events to every region of the state in order to reach out to all people living with HIV. The aim of the Peer Support Groups is to enable all PLHIV to socialise with their peers in a safe place and in an environment which is non-judgmental. Creation of these community groups... Read more